diff --git a/boost-1.76.0-fix_multiprecision_issue_419-ppc64le.patch b/boost-1.76.0-fix_multiprecision_issue_419-ppc64le.patch
new file mode 100644
index 0000000..5cd6d40
--- /dev/null
+++ b/boost-1.76.0-fix_multiprecision_issue_419-ppc64le.patch
@@ -0,0 +1,27 @@
+From d1343f28dcbe25b100b082b34775bd92ead4602c Mon Sep 17 00:00:00 2001
+From: jzmaddock <john@johnmaddock.co.uk>
+Date: Tue, 25 Jan 2022 09:27:40 +0000
+Subject: [PATCH] Update gcc Intel intrinsic usage config. Fixes
+ https://github.com/boostorg/multiprecision/issues/419.
+
+---
+ include/boost/multiprecision/cpp_int/intel_intrinsics.hpp | 6 +++++-
+ 1 file changed, 5 insertions(+), 1 deletion(-)
+
+diff --git a/include/boost/multiprecision/cpp_int/intel_intrinsics.hpp b/include/boost/multiprecision/cpp_int/intel_intrinsics.hpp
+index eb4624bb4..37717cd51 100644
+--- a/include/boost/multiprecision/cpp_int/intel_intrinsics.hpp
++++ b/include/boost/multiprecision/cpp_int/intel_intrinsics.hpp
+@@ -19,7 +19,11 @@
+ // If this is GCC/clang, then check that the actual intrinsic exists:
+ //
+ #if defined(__has_builtin) && defined(__GNUC__)
+-#if !__has_builtin(__builtin_ia32_addcarryx_u64) && defined(BOOST_MP_HAS_IMMINTRIN_H) && !(defined(BOOST_GCC) && (__GNUC__ >= 9))
++#if !__has_builtin(__builtin_ia32_addcarryx_u64) && defined(BOOST_MP_HAS_IMMINTRIN_H) \
++   && !(defined(BOOST_GCC) && (__GNUC__ >= 9) \
++      && (defined(__amd64__) || defined(__amd64) || defined(__x86_64__) || defined(__x86_64)\
++          || defined(i386) || defined(__i386) || defined(__i386__) || defined(_M_AMD64) \
++          || defined(_M_X64) || defined(__amd64__) || defined(_M_X64)))
+ #undef BOOST_MP_HAS_IMMINTRIN_H
+ #endif
+ #elif defined(BOOST_MP_HAS_IMMINTRIN_H) && defined(__GNUC__) && !(defined(BOOST_GCC) && (__GNUC__ >= 9))
diff --git a/boost.spec b/boost.spec
index fa3e2dc..5928a44 100644
--- a/boost.spec
+++ b/boost.spec
@@ -42,7 +42,7 @@ Name: boost
 %global real_name boost
 Summary: The free peer-reviewed portable C++ source libraries
 Version: 1.76.0
-Release: 7%{?dist}
+Release: 8%{?dist}
 License: Boost and MIT and Python
 
 # Replace each . with _ in %%{version}
@@ -161,6 +161,10 @@ Patch101: boost-1.76.0-fix-duplicate-typedef-in-mp.patch
 # https://github.com/boostorg/random/issues/82
 Patch102: boost-1.76.0-random-test.patch
 
+# PR https://github.com/boostorg/multiprecision/pull/421
+# fixes ppc64le issue https://github.com/boostorg/multiprecision/issues/419
+Patch103: boost-1.76.0-fix_multiprecision_issue_419-ppc64le.patch
+
 %bcond_with tests
 %bcond_with docs_generated
 
@@ -685,6 +689,7 @@ find ./boost -name '*.hpp' -perm /111 | xargs chmod a-x
 %patch100 -p1
 %patch101 -p1
 %patch102 -p1
+%patch103 -p2
 
 %build
 %set_build_flags
@@ -1296,6 +1301,10 @@ fi
 %{_mandir}/man1/b2.1*
 
 %changelog
+* Tue Feb  1 2022 Laurent Rineau <laurent.rineau@cgal.org> - 1.76.0-8
+- Add patch to fix Boost Multiprecision on ppc64le
+  https://github.com/boostorg/multiprecision/issues/419
+
 * Wed Jan 19 2022 Fedora Release Engineering <releng@fedoraproject.org> - 1.76.0-7
 - Rebuilt for https://fedoraproject.org/wiki/Fedora_36_Mass_Rebuild