diff --git a/ocaml-lablgtk-unix.patch b/ocaml-lablgtk-unix.patch
new file mode 100644
index 0000000..6692253
--- /dev/null
+++ b/ocaml-lablgtk-unix.patch
@@ -0,0 +1,26 @@
+--- lablgtk-2.18.13/configure.in.orig	2022-10-06 01:55:37.000000000 -0600
++++ lablgtk-2.18.13/configure.in	2023-09-27 12:16:38.789928991 -0600
+@@ -220,8 +220,8 @@ AC_MSG_RESULT(use $THREADS_LIB threads)
+ # Check for dll support
+ HAS_DLL_SUPPORT="no"
+ AC_MSG_CHECKING(for ocaml dll support)
+-if test -r "$OCAMLLIB/stublibs/dllunix.so" ||
+-   test -r "$OCAMLLIB/stublibs/dllunix.dll"
++if test -r "$OCAMLLIB/stublibs/dllunixnat.so" ||
++   test -r "$OCAMLLIB/stublibs/dllunixbyt.so"
+ then HAS_DLL_SUPPORT="yes"
+ fi
+ AC_MSG_RESULT($HAS_DLL_SUPPORT)
+--- lablgtk-2.18.13/configure.orig	2022-10-06 01:55:37.000000000 -0600
++++ lablgtk-2.18.13/configure	2023-09-27 13:31:10.122363877 -0600
+@@ -3172,8 +3172,8 @@ printf "%s\n" "use $THREADS_LIB threads"
+ HAS_DLL_SUPPORT="no"
+ { printf "%s\n" "$as_me:${as_lineno-$LINENO}: checking for ocaml dll support" >&5
+ printf %s "checking for ocaml dll support... " >&6; }
+-if test -r "$OCAMLLIB/stublibs/dllunix.so" ||
+-   test -r "$OCAMLLIB/stublibs/dllunix.dll"
++if test -r "$OCAMLLIB/stublibs/dllunixnat.so" ||
++   test -r "$OCAMLLIB/stublibs/dllunixbyt.so"
+ then HAS_DLL_SUPPORT="yes"
+ fi
+ { printf "%s\n" "$as_me:${as_lineno-$LINENO}: result: $HAS_DLL_SUPPORT" >&5
diff --git a/ocaml-lablgtk.spec b/ocaml-lablgtk.spec
index d2fc6d3..07207bf 100644
--- a/ocaml-lablgtk.spec
+++ b/ocaml-lablgtk.spec
@@ -22,6 +22,8 @@ Patch0:         %{name}-svgz.patch
 Patch1:         %{name}-precious.patch
 # Adapt to OCaml 5
 Patch2:         %{name}-ocaml5.patch
+# Adapt to new paths to Unix library in OCaml 5.1.0
+Patch3:         %{name}-unix.patch
 
 BuildRequires:  help2man
 BuildRequires:  make
@@ -29,6 +31,7 @@ BuildRequires:  ocaml >= 4.06
 BuildRequires:  ocaml-camlp-streams-devel
 BuildRequires:  ocaml-findlib >= 1.2.1
 BuildRequires:  ocaml-ocamldoc
+BuildRequires:  ocaml-rpm-macros
 BuildRequires:  pkgconfig(gtk+-2.0)
 BuildRequires:  pkgconfig(gtksourceview-2.0)
 BuildRequires:  pkgconfig(gtkspell-2.0)
@@ -38,7 +41,6 @@ BuildRequires:  pkgconfig(librsvg-2.0)
 BuildRequires:  pkgconfig(ncurses)
 BuildRequires:  pkgconfig(xmu)
 BuildRequires:  pkgconfig(zlib)
-BuildRequires:  python3
 
 %global __ocaml_requires_opts -i GtkSourceView2_types
 
@@ -149,6 +151,9 @@ sed -i '/propcc/d;/varcc/d' .ofiles
 
 
 %changelog
+* Wed Oct  4 2023 Jerry James <loganjerry@gmail.com> - 2.18.13-6
+- Add patch for new Unix library name in OCaml 5.1.0
+
 * Thu Jul 20 2023 Fedora Release Engineering <releng@fedoraproject.org> - 2.18.13-6
 - Rebuilt for https://fedoraproject.org/wiki/Fedora_39_Mass_Rebuild