diff --git a/.cvsignore b/.cvsignore
index 69e3f4a..87ef77b 100644
--- a/.cvsignore
+++ b/.cvsignore
@@ -1 +1 @@
-biopython-1.44.tar.gz
+biopython-1.45.tar.gz
diff --git a/python-biopython.spec b/python-biopython.spec
index b1a13c1..fcfe536 100644
--- a/python-biopython.spec
+++ b/python-biopython.spec
@@ -2,8 +2,8 @@
 %{!?python_sitearch: %define python_sitearch %(%{__python} -c "from distutils.sysconfig import get_python_lib; print get_python_lib(1)")}
 
 Name:             python-biopython
-Version:          1.44
-Release:          3%{?dist}
+Version:          1.45
+Release:          1%{?dist}
 Summary:          Python tools for computational molecular biology
 Source0:          http://biopython.org/DIST/biopython-%{version}.tar.gz
 License:          MIT
@@ -74,6 +74,12 @@ rm -rf $RPM_BUILD_ROOT
 %{python_sitearch}/BioSQL/*
 
 %changelog
+* Sun Mar 23 2008 Alex Lancaster <alexlan[AT]fedoraproject org> - 1.45-1
+- Update to latest upstream (1.45)
+
+* Sat Feb  9 2008 Alex Lancaster <alexlan[AT]fedoraproject org> - 1.44-4
+- rebuilt for GCC 4.3 as requested by Fedora Release Engineering
+
 * Thu Dec 13 2007 Alex Lancaster <alexlan[AT]fedoraproject.org> 1.44-3
 - Include eggs in file list for F9+
 
diff --git a/sources b/sources
index 9b0c241..1f04be2 100644
--- a/sources
+++ b/sources
@@ -1 +1 @@
-762c7a358af9dc58b712b8b4bb99d0c2  biopython-1.44.tar.gz
+049ff32be28297b77c25624082118629  biopython-1.45.tar.gz